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Inference of differential key regulatory networks and mechanistic drug repurposing candidates from scRNA-seq data with SCANet
MOTIVATION: The reconstruction of small key regulatory networks that explain the differences in the development of cell (sub)types from single-cell RNA sequencing is a yet unresolved computational problem. RESULTS: To this end, we have developed SCANet, an all-in-one package for single-cell profilin...
Autores principales: | Oubounyt, Mhaned, Adlung, Lorenz, Patroni, Fabio, Wenke, Nina Kerstin, Maier, Andreas, Hartung, Michael, Baumbach, Jan, Elkjaer, Maria L |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10628438/ https://www.ncbi.nlm.nih.gov/pubmed/37862243 http://dx.doi.org/10.1093/bioinformatics/btad644 |
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