Human ovarian aging is characterized by oxidative damage and mitochondrial dysfunction

STUDY QUESTION: Are human ovarian aging and the age-related female fertility decline caused by oxidative stress and mitochondrial dysfunction in oocytes? SUMMARY ANSWER: We found oxidative damage in oocytes of advanced maternal age, even at the primordial follicle stage, and confirmed mitochondrial...

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Detalles Bibliográficos
Autores principales: Smits, Myrthe A J, Schomakers, Bauke V, van Weeghel, Michel, Wever, Eric J M, Wüst, Rob C I, Dijk, Frederike, Janssens, Georges E, Goddijn, Mariëtte, Mastenbroek, Sebastiaan, Houtkooper, Riekelt H, Hamer, Geert
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2023
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10628503/
https://www.ncbi.nlm.nih.gov/pubmed/37671592
http://dx.doi.org/10.1093/humrep/dead177

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10628503/
https://www.ncbi.nlm.nih.gov/pubmed/37671592
http://dx.doi.org/10.1093/humrep/dead177

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