ONECUT1 variants beyond type 1 and type 2 diabetes: exploring clinical diversity and epigenetic associations in Arab cohorts

ONECUT1 gene, encoding hepatocyte nuclear factor 6, is involved in pancreas and liver development. ONECUT1 mutations impair the function of pancreatic β-cells and control a transcriptional/epigenetic machinery regulating endocrine development. Homozygous nonsense and missense mutations at ONECUT1_p....

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Detalles Bibliográficos
Autores principales: Dashti, Mohammed, Nizam, Rasheeba, John, Sumi Elsa, Melhem, Motasem, Channanath, Arshad, Alkandari, Hessa, Thanaraj, Thangavel Alphonse, Al-Mulla, Fahd
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Genetics
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10628528/
https://www.ncbi.nlm.nih.gov/pubmed/37941991
http://dx.doi.org/10.3389/fgene.2023.1254833

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10628528/
https://www.ncbi.nlm.nih.gov/pubmed/37941991
http://dx.doi.org/10.3389/fgene.2023.1254833

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