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Multiscale modeling of drug resistance in glioblastoma with gene mutations and angiogenesis

Drug resistance is a prominent impediment to the efficacy of targeted therapies across various cancer types, including glioblastoma (GBM). However, comprehending the intricate intracellular and extracellular mechanisms underlying drug resistance remains elusive. Empirical investigations have elucida...

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Detalles Bibliográficos
Autores principales: Yang, Heng, Lin, Haofeng, Sun, Xiaoqiang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Research Network of Computational and Structural Biotechnology 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10628546/
https://www.ncbi.nlm.nih.gov/pubmed/37941656
http://dx.doi.org/10.1016/j.csbj.2023.10.037