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Predicting Response to Antibody Drug Conjugates: A Focus on Antigens’ Targetability

Antibody-drug conjugates (ADCs) represent a cornerstone in the treatment of many cancers nowadays. ADCs fulfill their function by binding a target on tumor cell membrane to deliver a cytotoxic payload; in addition, those moieties capable of crossing cancer cell membranes can achieve near-by cells th...

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Detalles Bibliográficos
Autores principales: Ascione, Liliana, Crimini, Edoardo, Trapani, Dario, Marra, Antonio, Criscitiello, Carmen, Curigliano, Giuseppe
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10628585/
https://www.ncbi.nlm.nih.gov/pubmed/37665782
http://dx.doi.org/10.1093/oncolo/oyad246