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Antimicrobial peptide 2K4L disrupts the membrane of multidrug-resistant Acinetobacter baumannii and protects mice against sepsis

Antimicrobial peptides represent a promising therapeutic alternative for the treatment of antibiotic-resistant bacterial infections. 2K4L is a rationally-designed analog of a short peptide temporin-1CEc, a natural peptide isolated and purified from the skin secretions of the Chinese brown frog Rana...

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Detalles Bibliográficos
Autores principales: Ji, Fangyu, Tian, Guoxu, Shang, Dejing, Jiang, Fengquan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10628664/
https://www.ncbi.nlm.nih.gov/pubmed/37942076
http://dx.doi.org/10.3389/fmicb.2023.1258469