Tumor-targeted delivery of lnc antisense RNA against RCAS1 by live-attenuated tryptophan-auxotrophic Salmonella inhibited 4T1 breast tumors and metastasis in mice

Emerging chemo- and radiotherapy resistance exacerbated the cancer risk and necessitated novel treatment strategies. Although RNA therapeutics against pro-oncogenic genes are highly effective, tumor-specific delivery remains a barrier to the implementation of this valuable tool. In this study, we re...

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Detalles Bibliográficos
Autores principales: Sivasankar, Chandran, Hewawaduge, Chamith, Muthuramalingam, Pandiyan, Lee, John Hwa
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society of Gene & Cell Therapy 2023
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10628790/
https://www.ncbi.nlm.nih.gov/pubmed/37941832
http://dx.doi.org/10.1016/j.omtn.2023.102053

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10628790/
https://www.ncbi.nlm.nih.gov/pubmed/37941832
http://dx.doi.org/10.1016/j.omtn.2023.102053

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