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Development of a novel Guinea Pig model producing transgenerational endothelial transcriptional changes driven by maternal food restriction and a second metabolic insult of high fat diet

Developmental programming of chronic adverse cardiovascular health outcomes has been studied both using numerous human populations and an array of animal models. However, the mechanisms that produce transgenerational effects have been difficult to study due to a lack of developmentally relevant mode...

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Detalles Bibliográficos
Autores principales: Le, Hillary H., Hagen, Matthew W., Louey, Samantha, Tavori, Hagai, Thornburg, Kent L., Giraud, George D., Hinds, Monica T., Barnes, Anthony P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10628814/
https://www.ncbi.nlm.nih.gov/pubmed/37942229
http://dx.doi.org/10.3389/fphys.2023.1266444