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Development of a novel Guinea Pig model producing transgenerational endothelial transcriptional changes driven by maternal food restriction and a second metabolic insult of high fat diet
Developmental programming of chronic adverse cardiovascular health outcomes has been studied both using numerous human populations and an array of animal models. However, the mechanisms that produce transgenerational effects have been difficult to study due to a lack of developmentally relevant mode...
Autores principales: | Le, Hillary H., Hagen, Matthew W., Louey, Samantha, Tavori, Hagai, Thornburg, Kent L., Giraud, George D., Hinds, Monica T., Barnes, Anthony P. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10628814/ https://www.ncbi.nlm.nih.gov/pubmed/37942229 http://dx.doi.org/10.3389/fphys.2023.1266444 |
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