Effects of hepatic mitochondrial pyruvate carrier deficiency on de novo lipogenesis and gluconeogenesis in mice

The liver coordinates the systemic response to nutrient deprivation and availability by producing glucose from gluconeogenesis during fasting and synthesizing lipids via de novo lipogenesis (DNL) when carbohydrates are abundant. Mitochondrial pyruvate metabolism is thought to play important roles in...

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Detalles Bibliográficos
Autores principales: Yiew, Nicole K.H., Deja, Stanislaw, Ferguson, Daniel, Cho, Kevin, Jarasvaraparn, Chaowapong, Jacome-Sosa, Miriam, Lutkewitte, Andrew J., Mukherjee, Sandip, Fu, Xiaorong, Singer, Jason M., Patti, Gary J., Burgess, Shawn C., Finck, Brian N.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10628847/
https://www.ncbi.nlm.nih.gov/pubmed/37942005
http://dx.doi.org/10.1016/j.isci.2023.108196

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10628847/
https://www.ncbi.nlm.nih.gov/pubmed/37942005
http://dx.doi.org/10.1016/j.isci.2023.108196

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