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Investigation of new ferrocenyl-artesunate derivatives as antiparasitics

Artesunate (Ars) is a semisynthetic antimalarial drug and is a part of the artemisinin-based combination therapy arsenal employed for malaria treatment. The drug functions mainly by activation of its endoperoxide bridge leading to increased oxidative stress in malaria parasites. The purpose of this...

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Detalles Bibliográficos
Autores principales: Munnik, Brandon L., Kaschula, Catherine H., Harding, Clare R., Chellan, Prinessa
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society of Chemistry 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10628858/
https://www.ncbi.nlm.nih.gov/pubmed/37681434
http://dx.doi.org/10.1039/d3dt02254d