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MALAT1 promotes FOXA1 degradation by competitively binding to miR-216a-5p and enhancing neuroendocrine differentiation in prostate cancer

OBJECTIVES: Prostate cancer (PC) is a leading cause of cancer-related death in males worldwide. Neuroendocrine differentiation (NED) is a feature of PC that often goes undetected and is associated with poor patient outcomes. Long non-coding RNAs (lncRNAs), microRNAs (miRNAs/miRs), and messenger RNAs...

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Detalles Bibliográficos
Autores principales: Zeng, Fanchang, Li, Daoyuan, Kang, Xinli, Wu, Qinghui, Song, Mi, Ou, Zhewen, Yang, Zuobing, Yang, Jing, Luo, Liumei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Neoplasia Press 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10628887/
http://dx.doi.org/10.1016/j.tranon.2023.101807