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MALAT1 promotes FOXA1 degradation by competitively binding to miR-216a-5p and enhancing neuroendocrine differentiation in prostate cancer
OBJECTIVES: Prostate cancer (PC) is a leading cause of cancer-related death in males worldwide. Neuroendocrine differentiation (NED) is a feature of PC that often goes undetected and is associated with poor patient outcomes. Long non-coding RNAs (lncRNAs), microRNAs (miRNAs/miRs), and messenger RNAs...
Autores principales: | Zeng, Fanchang, Li, Daoyuan, Kang, Xinli, Wu, Qinghui, Song, Mi, Ou, Zhewen, Yang, Zuobing, Yang, Jing, Luo, Liumei |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Neoplasia Press
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10628887/ http://dx.doi.org/10.1016/j.tranon.2023.101807 |
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