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Melatonin inhibits Japanese encephalitis virus replication and neurotoxicity via calcineurin-autophagy pathways

BACKGROUND: Japanese encephalitis virus (JEV) is a mosquito-borne flavivirus that has no specific treatment except for supportive medical care. JEV is a neurotropic virus that affects the nervous system and triggers inflammation in the brain. METHODS: Melatonin is used as a sleep-inducing agent in n...

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Detalles Bibliográficos
Autores principales: Moon, Ji-Hong, Hong, Jeong-Min, Seol, Jae-Won, Park, Byung-Yong, Eo, Seong Kug, Park, Sang-Youel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10629071/
https://www.ncbi.nlm.nih.gov/pubmed/37932682
http://dx.doi.org/10.1186/s12868-023-00832-1