TROP2-directed nanobody-drug conjugate elicited potent antitumor effect in pancreatic cancer

BACKGROUND: Pancreatic cancer is a highly aggressive malignancy with limited treatment options and a poor prognosis. Trophoblast cell surface antigen 2 (TROP2), a cell surface antigen overexpressed in the tumors of more than half of pancreatic cancer patients, has been identified as a potential targ...

Descripción completa

Detalles Bibliográficos
Autores principales: Xu, Caili, Zhu, Min, Wang, Qian, Cui, Jiajun, Huang, Yuping, Huang, Xiting, Huang, Jing, Gai, Junwei, Li, Guanghui, Qiao, Peng, Zeng, Xian, Ju, Dianwen, Wan, Yakun, Zhang, Xuyao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10629078/
https://www.ncbi.nlm.nih.gov/pubmed/37932752
http://dx.doi.org/10.1186/s12951-023-02183-9

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10629078/
https://www.ncbi.nlm.nih.gov/pubmed/37932752
http://dx.doi.org/10.1186/s12951-023-02183-9

Ejemplares similares