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Ab initio protein structure prediction: the necessary presence of external force field as it is delivered by Hsp40 chaperone

BACKGROUND: The aqueous environment directs the protein folding process towards the generation of micelle-type structures, which results in the exposure of hydrophilic residues on the surface (polarity) and the concentration of hydrophobic residues in the center (hydrophobic core). Obtaining a struc...

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Detalles Bibliográficos
Autores principales: Roterman, Irena, Stapor, Katarzyna, Konieczny, Leszek
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10629080/
https://www.ncbi.nlm.nih.gov/pubmed/37932669
http://dx.doi.org/10.1186/s12859-023-05545-0