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Axially Chiral 2-Hydroxybiaryls by Palladium-Catalyzed Enantioselective C–H Activation

[Image: see text] This article describes the discovery and development of a palladium-catalyzed asymmetric C–H olefination of 2-hydroxybiaryls. The strategy allows a direct assembly of optically active, axially chiral 2-substituted-2′-hydroxybiaryls from readily available precursors and demonstrates...

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Detalles Bibliográficos
Autores principales: Losada, Pablo, Goicoechea, Laura, Mascareñas, José Luis, Gulías, Moisés
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2023
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10629138/
https://www.ncbi.nlm.nih.gov/pubmed/37942264
http://dx.doi.org/10.1021/acscatal.3c03867