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METTL3-mediated m6A methylation regulates ovarian cancer progression by recruiting myeloid-derived suppressor cells

BACKGROUND: Ovarian cancer (OC) typically develops an immunosuppressive microenvironment by funtional changes of host immune cells. Dysregulated m6A level is associated with cancer progression via the intrinsic oncogenic pathways. However, the role of m6A in regulating host immune cell function duri...

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Detalles Bibliográficos
Autores principales: Wang, Jinyong, Ling, Dakai, Shi, Lulin, Li, Huayun, Peng, Minhua, Wen, Huihong, Liu, Tao, Liang, Ruifang, Lin, Yongjian, Wei, Laiyou, Zhang, Guangzhi, Chen, Shanze
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10629157/
https://www.ncbi.nlm.nih.gov/pubmed/37932814
http://dx.doi.org/10.1186/s13578-023-01149-6