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Abnormal expression of PRKAG2-AS results in dysfunction of cardiomyocytes through regulating PRKAG2 transcription by interacting with PPARG

The role of PRKAG2 in the maintenance of heart function is well established, but little is known about how PRKAG2 is regulated in cardiomyocytes. In this study, we investigated the role of the lncRNA PRKAG2-AS, which is present at the PRKAG2 promoter, in the regulation of PRKAG2 expression. PRKAG2-A...

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Detalles Bibliográficos
Autores principales: Song, Xiao-Wei, Su, Ting, Li, Bo, Huang, Yun-Jie, He, Wen-Xia, Jiang, Li-Li, Li, Chang-Jin, Huang, Song-Qun, Li, Song-Hua, Guo, Zhi-Fu, Wu, Hong, Zhang, Bi-Li
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10629191/
https://www.ncbi.nlm.nih.gov/pubmed/37932845
http://dx.doi.org/10.1186/s13148-023-01591-w