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Genomic characterization of IDH-mutant astrocytoma progression to grade 4 in the treatment setting

As the progression of low-grade diffuse astrocytomas into grade 4 tumors significantly impacts patient prognosis, a better understanding of this process is of paramount importance for improved patient care. In this project, we analyzed matched IDH-mutant astrocytomas before and after progression to...

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Detalles Bibliográficos
Autores principales: Rautajoki, Kirsi J., Jaatinen, Serafiina, Hartewig, Anja, Tiihonen, Aliisa M., Annala, Matti, Salonen, Iida, Valkonen, Masi, Simola, Vili, Vuorinen, Elisa M., Kivinen, Anni, Rauhala, Minna J., Nurminen, Riikka, Maass, Kendra K., Lahtela, Sirpa-Liisa, Jukkola, Arja, Yli-Harja, Olli, Helén, Pauli, Pajtler, Kristian W., Ruusuvuori, Pekka, Haapasalo, Joonas, Zhang, Wei, Haapasalo, Hannu, Nykter, Matti
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10629206/
https://www.ncbi.nlm.nih.gov/pubmed/37932833
http://dx.doi.org/10.1186/s40478-023-01669-9