Immobilization of Trifluoromethyl-Substituted Pyridine-Oxazoline Ligand and Its Application in Asymmetric Continuous Flow Synthesis of Benzosultams

[Image: see text] This study presents an improved synthetic route to ligand (S)-4-(tert-butyl)-2-(5-(trifluoromethyl)pyridin-2-yl)-4,5-dihydrooxazole and its application as a highly active and enantioselective catalyst in the addition of arylboronic acids to cyclic N-sulfonylketimines. Immobilizatio...

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Detalles Bibliográficos
Autores principales: Kocúrik, Martin, Bartáček, Jan, Drabina, Pavel, Váňa, Jiří, Svoboda, Jan, Husáková, Lenka, Finger, Vladimír, Hympánová, Michaela, Sedlák, Miloš
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2023
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10629231/
https://www.ncbi.nlm.nih.gov/pubmed/37823216
http://dx.doi.org/10.1021/acs.joc.3c01671

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10629231/
https://www.ncbi.nlm.nih.gov/pubmed/37823216
http://dx.doi.org/10.1021/acs.joc.3c01671

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