Topical Administration of Verapamil in Poly(ethylene glycol)-Modified Liposomes for Enhanced Sinonasal Tissue Residence in Chronic Rhinosinusitis: Ex Vivo and In Vivo Evaluations

[Image: see text] Verapamil is a calcium channel blocker that holds promise for the therapy of chronic rhinosinusitis (CRS) with and without nasal polyps. The verapamil-induced side effects limit its tolerated dose via the oral route, underscoring the usefulness of localized intranasal administratio...

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Detalles Bibliográficos
Autores principales: Taha, Maie S., Kutlehria, Shallu, D’Souza, Anisha, Bleier, Benjamin S., Amiji, Mansoor M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2023
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10629233/
https://www.ncbi.nlm.nih.gov/pubmed/36744718
http://dx.doi.org/10.1021/acs.molpharmaceut.2c00943

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10629233/
https://www.ncbi.nlm.nih.gov/pubmed/36744718
http://dx.doi.org/10.1021/acs.molpharmaceut.2c00943

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