Cell-free DNA-based prenatal screening via rolling circle amplification: Identifying and resolving analytic issues

OBJECTIVE: A rolling circle amplification (RCA) based commercial methodology using cell-free (cf)DNA to screen for common trisomies became available in 2018. Relevant publications documented high detection but with a higher than expected 1% false positive rate. Preliminary evidence suggested assay v...

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Detalles Bibliográficos
Autores principales: Palomaki, Glenn E, Lambert-Messerlian, Geralyn M, Fullerton, Donna, Hegde, Madhuri, Conotte, Stéphanie, Saidel, Matthew L, Jani, Jacques C
Formato: Online Artículo Texto
Lenguaje:English
Publicado: SAGE Publications 2023
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10629251/
https://www.ncbi.nlm.nih.gov/pubmed/37194254
http://dx.doi.org/10.1177/09691413231173315

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10629251/
https://www.ncbi.nlm.nih.gov/pubmed/37194254
http://dx.doi.org/10.1177/09691413231173315

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