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Orbitrap Mass Spectrometry and High-Field Asymmetric Waveform Ion Mobility Spectrometry (FAIMS) Enable the in-Depth Analysis of Human Serum Proteoforms

[Image: see text] Blood serum and plasma are arguably the most commonly analyzed clinical samples, with dozens of proteins serving as validated biomarkers for various human diseases. Top-down proteomics may provide additional insights into disease etiopathogenesis since this approach focuses on prot...

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Detalles Bibliográficos
Autores principales: Kline, Jake T., Belford, Michael W., Boeser, Cornelia L., Huguet, Romain, Fellers, Ryan T., Greer, Joseph B., Greer, Sylvester M., Horn, David M., Durbin, Kenneth R., Dunyach, Jean-Jacques, Ahsan, Nagib, Fornelli, Luca
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2023
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10629265/
https://www.ncbi.nlm.nih.gov/pubmed/37774690
http://dx.doi.org/10.1021/acs.jproteome.3c00488