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Effect of Swine Glyco-humanized Polyclonal Neutralizing Antibody on Survival and Respiratory Failure in Patients Hospitalized With Severe COVID-19: A Randomized, Placebo-Controlled Trial

BACKGROUND: We evaluated the safety and efficacy of XAV-19, an antispike glyco-humanized swine polyclonal neutralizing antibody in patients hospitalized with severe coronavirus disease 2019 (COVID-19). METHODS: This phase 2b clinical trial enrolled adult patients from 34 hospitals in France. Eligibl...

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Detalles Bibliográficos
Autores principales: Gaborit, Benjamin, Vanhove, Bernard, Lacombe, Karine, Guimard, Thomas, Hocqueloux, Laurent, Perrier, Ludivine, Dubee, Vincent, Ferre, Virginie, Bressollette, Celine, Josien, Régis, Thuaut, Aurélie Le, Vibet, Marie-Anne, Jobert, Alexandra, Dailly, Eric, Ader, Florence, Brouard, Sophie, Duvaux, Odile, Raffi, François
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10629360/
https://www.ncbi.nlm.nih.gov/pubmed/37942459
http://dx.doi.org/10.1093/ofid/ofad525