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One-pot four-component synthesis of novel isothiourea-ethylene-tethered-piperazine derivatives

An efficient metal-free four-component approach for the synthesis of piperazine derivatives tethered to an isothiourea group through an ethylene link was developed. 1,4-Diazabicyclo[2.2.2]octane (DABCO) salts, generated in situ through the reactions of DABCO with various alkyl bromides, reacted with...

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Detalles Bibliográficos
Autores principales: Hajizadeh, Fatima, Mojtahedi, Mohammad M., Abaee, M. Saeed
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society of Chemistry 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10629393/
https://www.ncbi.nlm.nih.gov/pubmed/37942451
http://dx.doi.org/10.1039/d3ra06678a