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The multiple activations in budding yeast S-phase checkpoint are Poisson processes

Eukaryotic cells activate the S-phase checkpoint signal transduction pathway in response to DNA replication stress. Affected by the noise in biochemical reactions, such activation process demonstrates cell-to-cell variability. Here, through the analysis of microfluidics-integrated time-lapse imaging...

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Detalles Bibliográficos
Autores principales: Gao, Xin, Zhou, Peijie, Li, Fangting
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10629469/
https://www.ncbi.nlm.nih.gov/pubmed/37941810
http://dx.doi.org/10.1093/pnasnexus/pgad342