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The autotaxin-LPA axis promotes membrane trafficking and secretion in yolk sac visceral endoderm cells

Autotaxin, encoded by the Enpp2 gene, is an exoenzyme that produces lysophosphatidic acid, thereby regulating many biologic functions. We previously reported that Enpp2 mRNA was abundantly expressed in yolk sac visceral endoderm (VE) cells and that Enpp2(−/−) mice were lethal at embryonic day 9.5 ow...

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Detalles Bibliográficos
Autores principales: Koike, Seiichi, Keino-Masu, Kazuko, Tanimoto, Yoko, Takahashi, Satoru, Masu, Masayuki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Company of Biologists Ltd 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10629499/
https://www.ncbi.nlm.nih.gov/pubmed/37795611
http://dx.doi.org/10.1242/bio.060081