Increased neutralization potency and breadth elicited by a SARS-CoV-2 mRNA vaccine forming virus-like particles

Vaccines have played a fundamental role in the control of infectious diseases. We previously developed a messenger RNA (mRNA) vaccine against HIV-1 that forms virus-like particles (VLPs) through coexpression of the viral envelope with Gag. Here, we applied the same principle to the design of a VLP-f...

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Detalles Bibliográficos
Autores principales: Zhang, Peng, Falcone, Samantha, Tsybovsky, Yaroslav, Singh, Mamta, Gopan, Vinay, Miao, Huiyi, Seo, Yuna, Rogers, Denise, Renzi, Isabella, Lai, Yen-Ting, Narayanan, Elisabeth, Stewart-Jones, Guillaume, Himansu, Sunny, Carfi, Andrea, Fauci, Anthony S., Lusso, Paolo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: National Academy of Sciences 2023
Materias:
Biological Sciences
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10629519/
https://www.ncbi.nlm.nih.gov/pubmed/37428933
http://dx.doi.org/10.1073/pnas.2305896120

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10629519/
https://www.ncbi.nlm.nih.gov/pubmed/37428933
http://dx.doi.org/10.1073/pnas.2305896120

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