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Increased neutralization potency and breadth elicited by a SARS-CoV-2 mRNA vaccine forming virus-like particles
Vaccines have played a fundamental role in the control of infectious diseases. We previously developed a messenger RNA (mRNA) vaccine against HIV-1 that forms virus-like particles (VLPs) through coexpression of the viral envelope with Gag. Here, we applied the same principle to the design of a VLP-f...
Autores principales: | Zhang, Peng, Falcone, Samantha, Tsybovsky, Yaroslav, Singh, Mamta, Gopan, Vinay, Miao, Huiyi, Seo, Yuna, Rogers, Denise, Renzi, Isabella, Lai, Yen-Ting, Narayanan, Elisabeth, Stewart-Jones, Guillaume, Himansu, Sunny, Carfi, Andrea, Fauci, Anthony S., Lusso, Paolo |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
National Academy of Sciences
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10629519/ https://www.ncbi.nlm.nih.gov/pubmed/37428933 http://dx.doi.org/10.1073/pnas.2305896120 |
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