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ToxR activates the Vibrio cholerae virulence genes by tethering DNA to the membrane through versatile binding to multiple sites

ToxR, a Vibrio cholerae transmembrane one-component signal transduction factor, lies within a regulatory cascade that results in the expression of ToxT, toxin coregulated pilus, and cholera toxin. While ToxR has been extensively studied for its ability to activate or repress various genes in V. chol...

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Detalles Bibliográficos
Autores principales: Canals, Albert, Pieretti, Simone, Muriel-Masanes, Mireia, El Yaman, Nour, Plecha, Sarah C., Thomson, Joshua J., Fàbrega-Ferrer, Montserrat, Pérez-Luque, Rosa, Krukonis, Eric S., Coll, Miquel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: National Academy of Sciences 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10629549/
https://www.ncbi.nlm.nih.gov/pubmed/37428913
http://dx.doi.org/10.1073/pnas.2304378120