Spt5 interacts genetically with Myc and is limiting for brain tumor growth in Drosophila

The transcription factor SPT5 physically interacts with MYC oncoproteins and is essential for efficient transcriptional activation of MYC targets in cultured cells. Here, we use Drosophila to address the relevance of this interaction in a living organism. Spt5 displays moderate synergy with Myc in f...

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Detalles Bibliográficos
Autores principales: Hofstetter, Julia, Ogunleye, Ayoola, Kutschke, André, Buchholz, Lisa Marie, Wolf, Elmar, Raabe, Thomas, Gallant, Peter
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Life Science Alliance LLC 2023
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10629571/
https://www.ncbi.nlm.nih.gov/pubmed/37935464
http://dx.doi.org/10.26508/lsa.202302130

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10629571/
https://www.ncbi.nlm.nih.gov/pubmed/37935464
http://dx.doi.org/10.26508/lsa.202302130

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