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Diet-induced glial insulin resistance impairs the clearance of neuronal debris in Drosophila brain

Obesity significantly increases the risk of developing neurodegenerative disorders, yet the precise mechanisms underlying this connection remain unclear. Defects in glial phagocytic function are a key feature of neurodegenerative disorders, as delayed clearance of neuronal debris can result in infla...

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Detalles Bibliográficos
Autores principales: Alassaf, Mroj, Rajan, Akhila
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10629620/
https://www.ncbi.nlm.nih.gov/pubmed/37934726
http://dx.doi.org/10.1371/journal.pbio.3002359