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Serpin-1a and serpin-6 regulate the Toll pathway immune homeostasis by synergistically inhibiting the Spätzle-processing enzyme CLIP2 in silkworm, Bombyx mori

The Toll receptor signaling pathway is an important innate immune response of insects to pathogen infection; its extracellular signal transduction involves serine protease cascade activation. However, excessive or constitutive activation of the Toll pathway can be detrimental. Hence, the balance bet...

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Detalles Bibliográficos
Autores principales: Liu, Huawei, Xu, Jiahui, Wang, Luoling, Guo, Pengchao, Tang, Zhangchen, Sun, Xiaotong, Tang, Xin, Wang, Wei, Wang, Lingyan, Cao, Yang, Xia, Qingyou, Zhao, Ping
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10629668/
https://www.ncbi.nlm.nih.gov/pubmed/37851691
http://dx.doi.org/10.1371/journal.ppat.1011740