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The chromatin source-sink hypothesis: a shared mode of chromatin-mediated regulations

We propose that several chromatin-mediated regulatory processes are dominated by source-sink relationships in which factors operate as ‘sources’ to produce or provide a resource and compete with each other to occupy separate ‘sinks’. In this model, large portions of genomic DNA operate as ‘sinks’, w...

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Detalles Bibliográficos
Autores principales: Murphy, Patrick J., Berger, Frédéric
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Company of Biologists Ltd 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10629678/
https://www.ncbi.nlm.nih.gov/pubmed/37922125
http://dx.doi.org/10.1242/dev.201989