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Endothelial cell SMAD6 balances Alk1 function to regulate adherens junctions and hepatic vascular development
BMP signaling is crucial to blood vessel formation and function, but how pathway components regulate vascular development is not well-understood. Here, we find that inhibitory SMAD6 functions in endothelial cells to negatively regulate ALK1-mediated responses, and it is required to prevent vessel dy...
| Autores principales: | , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
The Company of Biologists Ltd
2023
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10629679/ https://www.ncbi.nlm.nih.gov/pubmed/37787089 http://dx.doi.org/10.1242/dev.201811 |