CCDC183 is essential for cytoplasmic invagination around the flagellum during spermiogenesis and male fertility

Sperm flagellum plays a crucial role in male fertility. Here, we generated Ccdc183 knockout mice using the CRISPR/Cas9 system to reveal the protein function of the testis-specific protein CCDC183 in spermiogenesis. We demonstrated that the absence of CCDC183 causes male infertility with morphologica...

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Detalles Bibliográficos
Autores principales: Shimada, Keisuke, Ikawa, Masahito
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Company of Biologists Ltd 2023
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10629680/
https://www.ncbi.nlm.nih.gov/pubmed/37882665
http://dx.doi.org/10.1242/dev.201724

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10629680/
https://www.ncbi.nlm.nih.gov/pubmed/37882665
http://dx.doi.org/10.1242/dev.201724

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