Contemporary human H3N2 influenza A viruses require a low threshold of suitable glycan receptors for efficient infection

Recent human H3N2 influenza A viruses have evolved to employ elongated glycans terminating in α2,6-linked sialic acid as their receptors. These glycans are displayed in low abundancies by (humanized) Madin-Darby Canine Kidney cells, which are commonly employed to propagate influenza A virus, resulti...

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Detalles Bibliográficos
Autores principales: Spruit, Cindy M, Sweet, Igor R, Maliepaard, Joshua C L, Bestebroer, Theo, Lexmond, Pascal, Qiu, Boning, Damen, Mirjam J A, Fouchier, Ron A M, Reiding, Karli R, Snijder, Joost, Herfst, Sander, Boons, Geert-Jan, de Vries, Robert P
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2023
Materias:
Regular Manuscripts
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10629718/
https://www.ncbi.nlm.nih.gov/pubmed/37471650
http://dx.doi.org/10.1093/glycob/cwad060

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10629718/
https://www.ncbi.nlm.nih.gov/pubmed/37471650
http://dx.doi.org/10.1093/glycob/cwad060

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