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Amyloid Beta Alters the Expression of microRNAs Regulating HMGCR and ABCA1 Genes in Astrocytes of C57BL/6J Mice

Dysregulation of brain cholesterol homeostasis causes the accumulation of extracellular protein deposits called amyloid plaques in the hippocampus which eventually leads to neuronal death, memory and learning deficits. The aim of the present study was to investigate the effect of beta amyloid on miR...

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Detalles Bibliográficos
Autores principales: Azizi Dariuni, Hossein, Karimi Darabi, Mehrnaz, Nazeri, Zahra, Azizidoost, Shirin, Kheiroallah, Alireza, Khedri, Azam, Cheraghzadeh, Maryam
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Babol University of Medical Sciences 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10629724/
https://www.ncbi.nlm.nih.gov/pubmed/37942261
http://dx.doi.org/10.22088/IJMCM.BUMS.12.1.30