Epithelial Yap/Taz are required for functional alveolar regeneration following acute lung injury

A hallmark of idiopathic pulmonary fibrosis (IPF) and other interstitial lung diseases is dysregulated repair of the alveolar epithelium. The Hippo pathway effector transcription factors YAP and TAZ are implicated as essential for type 1 and type 2 alveolar epithelial cell (AT1 and AT2) differentiat...

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Detalles Bibliográficos
Autores principales: DiGiovanni, Gianluca T., Han, Wei, Sherrill, Taylor P., Taylor, Chase J., Nichols, David S., Geis, Natalie M., Singha, Ujjal K., Calvi, Carla L., McCall, A. Scott, Dixon, Molly M., Liu, Yang, Jang, Ji-Hoon, Gutor, Sergey S., Polosukhin, Vasiliy V., Blackwell, Timothy S., Kropski, Jonathan A., Gokey, Jason J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Clinical Investigation 2023
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10629815/
https://www.ncbi.nlm.nih.gov/pubmed/37676731
http://dx.doi.org/10.1172/jci.insight.173374

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10629815/
https://www.ncbi.nlm.nih.gov/pubmed/37676731
http://dx.doi.org/10.1172/jci.insight.173374

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