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Modulation of protein-DNA binding reveals mechanisms of spatiotemporal gene control in early Drosophila embryos

It is well known that enhancers regulate the spatiotemporal expression of their target genes by recruiting transcription factors (TFs) to the cognate binding sites in the region. However, the role of multiple binding sites for the same TFs and their specific spatial arrangement in determining the ov...

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Detalles Bibliográficos
Autores principales: Syed, Sahla, Duan, Yifei, Lim, Bomyi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10629816/
https://www.ncbi.nlm.nih.gov/pubmed/37934571
http://dx.doi.org/10.7554/eLife.85997