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Genetic validation of PfFKBP35 as an antimalarial drug target

Plasmodium falciparum accounts for the majority of over 600,000 malaria-associated deaths annually. Parasites resistant to nearly all antimalarials have emerged and the need for drugs with alternative modes of action is thus undoubted. The FK506-binding protein PfFKBP35 has gained attention as a pro...

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Detalles Bibliográficos
Autores principales: Thommen, Basil T, Dziekan, Jerzy M, Achcar, Fiona, Tjia, Seth, Passecker, Armin, Buczak, Katarzyna, Gumpp, Christin, Schmidt, Alexander, Rottmann, Matthias, Grüring, Christof, Marti, Matthias, Bozdech, Zbynek, Brancucci, Nicolas MB
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10629825/
https://www.ncbi.nlm.nih.gov/pubmed/37934560
http://dx.doi.org/10.7554/eLife.86975