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Analysis of CDPK1 targets identifies a trafficking adaptor complex that regulates microneme exocytosis in Toxoplasma

Apicomplexan parasites use Ca(2+)-regulated exocytosis to secrete essential virulence factors from specialized organelles called micronemes. Ca(2+)-dependent protein kinases (CDPKs) are required for microneme exocytosis; however, the molecular events that regulate trafficking and fusion of microneme...

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Detalles Bibliográficos
Autores principales: Chan, Alex W, Broncel, Malgorzata, Yifrach, Eden, Haseley, Nicole R, Chakladar, Sundeep, Andree, Elena, Herneisen, Alice L, Shortt, Emily, Treeck, Moritz, Lourido, Sebastian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10629828/
https://www.ncbi.nlm.nih.gov/pubmed/37933960
http://dx.doi.org/10.7554/eLife.85654