Cargando…
Analysis of CDPK1 targets identifies a trafficking adaptor complex that regulates microneme exocytosis in Toxoplasma
Apicomplexan parasites use Ca(2+)-regulated exocytosis to secrete essential virulence factors from specialized organelles called micronemes. Ca(2+)-dependent protein kinases (CDPKs) are required for microneme exocytosis; however, the molecular events that regulate trafficking and fusion of microneme...
Autores principales: | Chan, Alex W, Broncel, Malgorzata, Yifrach, Eden, Haseley, Nicole R, Chakladar, Sundeep, Andree, Elena, Herneisen, Alice L, Shortt, Emily, Treeck, Moritz, Lourido, Sebastian |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
eLife Sciences Publications, Ltd
2023
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10629828/ https://www.ncbi.nlm.nih.gov/pubmed/37933960 http://dx.doi.org/10.7554/eLife.85654 |
Ejemplares similares
-
Analysis of CDPK1 targets identifies a trafficking adaptor complex that regulates microneme exocytosis in Toxoplasma
por: Chan, Alex W, et al.
Publicado: (2023) -
CDPK2A and CDPK1 form a signaling module upstream of Toxoplasma motility
por: Shortt, Emily, et al.
Publicado: (2023) -
The triumvirate of signaling molecules controlling Toxoplasma microneme exocytosis: Cyclic GMP, calcium, and phosphatidic acid
por: Bullen, Hayley E., et al.
Publicado: (2019) -
A conserved complex of microneme proteins mediates rhoptry discharge in Toxoplasma
por: Valleau, Dylan, et al.
Publicado: (2023) -
Screening the Toxoplasma kinome with high-throughput tagging (HiT) identifies a regulator of invasion and egress
por: Smith, Tyler A., et al.
Publicado: (2022)