Cargando…

Insights into RAG Evolution from the Identification of “Missing Link” Family A RAGL Transposons

A series of “molecular domestication” events are thought to have converted an invertebrate RAG-like (RAGL) transposase into the RAG1–RAG2 (RAG) recombinase, a critical enzyme for adaptive immunity in jawed vertebrates. The timing and order of these events are not well understood, in part because of...

Descripción completa

Detalles Bibliográficos
Autores principales: Martin, Eliza C, Le Targa, Lorlane, Tsakou-Ngouafo, Louis, Fan, Tzu-Pei, Lin, Che-Yi, Xiao, Jianxiong, Huang, Ziwen, Yuan, Shaochun, Xu, Anlong, Su, Yi-Hsien, Petrescu, Andrei-Jose, Pontarotti, Pierre, Schatz, David G
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10629977/
https://www.ncbi.nlm.nih.gov/pubmed/37850912
http://dx.doi.org/10.1093/molbev/msad232