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Polo样激酶1抑制剂在奥希替尼耐药的非小细胞肺癌细胞中的作用

OBJECTIVE: To investigate the effects of PLK1 inhibitors on osimertinib-resistant non-small cell lung carcinoma (NSCLC) cells and the anti-tumor effect combined with osimertinib. METHODS: An osimertinib resistant NCI-H1975 cell line was induced by exposure to gradually increasing drug concentrations...

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Detalles Bibliográficos
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 《浙江大学学报》编辑部 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10630054/
https://www.ncbi.nlm.nih.gov/pubmed/37899396
http://dx.doi.org/10.3724/zdxbyxb-2023-0305