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A farnesyl-dependent structural role for CENP-E in expansion of the fibrous corona

Correct chromosome segregation during cell division depends on proper connections between spindle microtubules and kinetochores. During prometaphase, kinetochores are temporarily covered with a dense protein meshwork known as the fibrous corona. Formed by oligomerization of ROD/ZW10/ZWILCH-SPINDLY (...

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Detalles Bibliográficos
Autores principales: Wu, Jingchao, Raas, Maximilian W.D., Alcaraz, Paula Sobrevals, Vos, Harmjan R., Tromer, Eelco C., Snel, Berend, Kops, Geert J.P.L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Rockefeller University Press 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10630089/
https://www.ncbi.nlm.nih.gov/pubmed/37934467
http://dx.doi.org/10.1083/jcb.202303007