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Population-level integration of single-cell datasets enables multi-scale analysis across samples

The increasing generation of population-level single-cell atlases has the potential to link sample metadata with cellular data. Constructing such references requires integration of heterogeneous cohorts with varying metadata. Here we present single-cell population level integration (scPoli), an open...

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Detalles Bibliográficos
Autores principales: De Donno, Carlo, Hediyeh-Zadeh, Soroor, Moinfar, Amir Ali, Wagenstetter, Marco, Zappia, Luke, Lotfollahi, Mohammad, Theis, Fabian J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group US 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10630133/
https://www.ncbi.nlm.nih.gov/pubmed/37813989
http://dx.doi.org/10.1038/s41592-023-02035-2