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Causal identification of single-cell experimental perturbation effects with CINEMA-OT

Recent advancements in single-cell technologies allow characterization of experimental perturbations at single-cell resolution. While methods have been developed to analyze such experiments, the application of a strict causal framework has not yet been explored for the inference of treatment effects...

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Detalles Bibliográficos
Autores principales: Dong, Mingze, Wang, Bao, Wei, Jessica, de O. Fonseca, Antonio H., Perry, Curtis J., Frey, Alexander, Ouerghi, Feriel, Foxman, Ellen F., Ishizuka, Jeffrey J., Dhodapkar, Rahul M., van Dijk, David
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group US 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10630139/
https://www.ncbi.nlm.nih.gov/pubmed/37919419
http://dx.doi.org/10.1038/s41592-023-02040-5