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Repeat-dose toxicity study of human umbilical cord mesenchymal stem cells in cynomolgus monkeys by intravenous and subcutaneous injection

Human umbilical cord mesenchymal stem cells (hUC-MSCs) are proposed for the treatment of acute lung injury and atopic dermatitis. To advance hUC-MSC entry into clinical trials, the effects of hUC-MSCs on the general toxicity, immune perturbation and toxicokinetic study of hUC-MSCs in cynomolgus monk...

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Detalles Bibliográficos
Autores principales: Pan, Wei, Gu, Liqiang, Yang, Hongzhong, Xu, Cong, Yang, Zhengbiao, Lu, Qijiong, Shi, Yuhua, Zhang, Lili, Shao, Jinjin, Chen, Yunxiang, Pan, Xin, Wu, Feifei, Pan, Ruolang, Liang, Jinfeng, Zhang, Lijiang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10630163/
https://www.ncbi.nlm.nih.gov/pubmed/38020919
http://dx.doi.org/10.3389/fcell.2023.1273723